abstract：:Small fields are more repeatedly used for radiation therapy as small segments in intensity-modulated radiotherapy or as in the form of independent fields in stereotactic radiosurgery and other novel equipment such as cyberknife and tomotherapy. Nevertheless, the application of small fields for radiotherapy of lung mak...

journal_title：Journal of cancer research and therapeutics

authors： Bagheri H,Soleimani A,Gharehaghaji N,Mesbahi A,Manouchehri F,Shekarchi B,Dormanesh B,Dadgar HA

更新日期：2017-04-01 00:00:00

abstract：BACKGROUND:Telomeres, which are bound with shelterin protein complex, play an important role in maintaining genomic stability and its dysfunction may lead to carcinogenesis. Here, we aimed to analyze whether shelterin complex gene expression and telomere length variation, play any role in gallbladder carcinogenesis. M...

journal_title：Journal of cancer research and therapeutics

authors： Poojary SS,Mishra G,Singh TD,Gupta S,Shrivastav BR,Tiwari PK

更新日期：2017-04-01 00:00:00

abstract：AIM:The aim of this study was to evaluate the effect of adding etoposide and ifosfamide chemotherapy drugs to treatment regimen of patients affected with osteosarcoma and to determine the clinical process and response to treatment during a follow-up period of 11 years. MATERIALS AND METHODS:Forty patients with osteosa...

journal_title：Journal of cancer research and therapeutics

authors： Aznab M,Hematti M

更新日期：2017-04-01 00:00:00

abstract：AIMS:Hereditary nonpolyposis colorectal cancer (HNPCC) is a subgroup of colorectal cancer (CRC) which should be differentiated because of the high risk for additional cancers and risk evaluation for other family members, especially for CRC. It is not practical to perform genetic testing for all CRC patients; therefore,...

journal_title：Journal of cancer research and therapeutics

authors： Kaya M,Basak F,Sisik A,Hasbahceci M,Bas G,Alimoglu O,Topal CS,Kir G

更新日期：2017-04-01 00:00:00

abstract：OBJECTIVE:The aim of the present study was to evaluate the feasibility and safety of laparoscopic surgery for endometrial cancer in aged patients and show the experiences of laparoscopic surgery for elderly endometrial cancer patients in Eastern China. MATERIALS AND METHODS:A total of 211 patients (≥60 years) with end...

journal_title：Journal of cancer research and therapeutics

authors： Liu SP,Cheng XW,Tian X,Zhang Q,Cui HY,Hua KQ

更新日期：2017-01-01 00:00:00

abstract：OBJECTIVE:The aim of the study was to investigate the expression of Twist, E-cadherin, and N-cadherin both in normal endometrium and in endometrioid adenocarcinoma tissues (NET and EAT), and further discuss the relationship between the proteins expression and the clinical parameters. METHODS:Seventy-six EAT and 50 NET...

journal_title：Journal of cancer research and therapeutics

authors： Xie X,Zheng X,Wang J,Chen L

更新日期：2017-01-01 00:00:00

abstract：:Tumors arising from Meckel's diverticulum (MD) reported in the literature are mainly carcinoid and gastrointestinal stromal tumors. We herein report a rare case of adenocarcinoma arising from intestinal mucosa in an MD with multiple liver metastases at the onset of symptoms. A 57-year-old female complaining of bloody ...

journal_title：Journal of cancer research and therapeutics

authors： Zhao Y,Yang X,Ye Y

更新日期：2017-01-01 00:00:00

abstract：INTRODUCTION:Treatment of proliferative diseases of the hematopoietic system involves, in most cases, chemotherapy combined with radiation therapy, which is intended to provide adequate immunosuppressant. Conventionally, total body irradiation (TBI) was used; however, total marrow irradiation (TMI) performed with helic...

journal_title：Journal of cancer research and therapeutics

authors： Konstanty E,Malicki J,Łagodowska K,Kowalik A

更新日期：2017-01-01 00:00:00

abstract：INTRODUCTION:Using physical wedges (PWs) to modify dose distribution and more homogeneous target coverage is a well-established technique. However, there are many problems with PWs known as beam hardening, which made them problematic. This can be overcome by dynamic wedges which do not filter beam. Comparison of physic...

journal_title：Journal of cancer research and therapeutics

authors： Geraily G,Sharafi N,Shirazi A,Esfehani M,Masoudifar M,Rajab BE

更新日期：2017-01-01 00:00:00

abstract：:Hemangiopericytomas (HPCs) are rare soft tissue tumors. The eyelid is a very uncommon site for these tumors, and an anaplastic variant of HPC in the eyelid has not been reported before. A 44-year-old male presented with complaints of slowly progressive, painless swelling on the inner aspect of the left upper eyelid fo...

journal_title：Journal of cancer research and therapeutics

authors： Ventrapati P,Pathy S,Gandhi AK,Kashyap S

更新日期：2017-01-01 00:00:00

abstract：BACKGROUND:Malignant fibrous histiocytoma (MFH) is an uncommon neoplasm of maxillary sinus. This study was designed to investigate the clinical courses and summarize the experience of the treatment outcomes. MATERIALS AND METHODS:This is a retrospective analysis which included patients with MFH of the maxillary sinus ...

journal_title：Journal of cancer research and therapeutics

authors： Huang H,Li D,Wang X,Wu Y,Liu S,Xu Z

更新日期：2017-01-01 00:00:00

abstract：AIM OF STUDY:The aim of this study was to analyze the clinical features and outcomes of thyroid carcinoma (TC) in children and adolescent population treated in our institution. MATERIALS AND METHODS:We gathered 43 TC patients 18 years of age or under initial diagnosed between 2009 and 2010 from two hospitals. Patient'...

journal_title：Journal of cancer research and therapeutics

authors： Pan JJ,Zhao L,Cheng R,Yang Y,Hu YH

更新日期：2017-01-01 00:00:00

abstract：OBJECTIVE:This study aimed to compare the dose difference in 125 I seed implantation between three-dimensional (3D) print template-guided operation and traditional implantation. MATERIALS AND METHODS:This study retrospectively analyzed 27 patients who underwent 125I seed implantation from August 2015 to December 2015 ...

journal_title：Journal of cancer research and therapeutics

authors： Hongtao Z,Xuemin D,Huimin Y,Zeyang W,Lijuan Z,Jinxin Z,Zezhou L,Aixia S,Juan W

更新日期：2016-12-01 00:00:00

abstract：OBJECTIVE:To evaluate the safety and efficacy of transcatheter arterial chemoembolization (TACE) combined with percutaneous microwave ablation (MWA) in the treatment of advanced hepatocellular carcinoma (HCC). MATERIALS AND METHODS:Three thousand cases of advanced HCC patients were randomly divided into two groups: 15...

journal_title：Journal of cancer research and therapeutics

authors： Li W,Man W,Guo H,Yang P

更新日期：2016-12-01 00:00:00

abstract：OBJECTIVE:The purpose of this meta-analysis was to evaluate the predictive value of cervical lymph node metastasis through sentinel lymph node biopsy (SLNB) in patients with oral cancer. MATERIALS AND METHODS:Two authors independently searched the databases of PubMed, Cochrane central register of controlled trials, EM...

journal_title：Journal of cancer research and therapeutics

authors： Lin R,Yan J,Liu W,Fan T,Tang L

更新日期：2016-12-01 00:00:00

abstract：OBJECTIVE:The aim of this study was to assess Ezrin expression in the primary hepatic carcinoma patients and associated with clinical, pathological characteristics. MATERIALS AND METHODS:Fifty-one patients with primary hepatocellular carcinoma (PHC) with completed clinical data were retrospectively analyzed in this st...

journal_title：Journal of cancer research and therapeutics

authors： Pan D,Wang S,Ye H,Xu S,Ye G

更新日期：2016-12-01 00:00:00

abstract：:Adjuvant treatment options for Stage I seminoma include active surveillance, chemotherapy, and radiotherapy. Active surveillance may not be ideal for the average Indian patient. Of the two accepted adjuvant therapy options, namely single-dose carboplatin chemotherapy and radiotherapy to the retroperitoneal nodes, thou...

journal_title：Journal of cancer research and therapeutics

authors： Yathiraj PH,Sharan K,Fernandes DJ,Vidyasagar MS

更新日期：2016-10-01 00:00:00

abstract：AIM:B-cell chronic lymphocytic leukemia (B-CLL) is the most common adult leukemia in the Western world and characterized by the progressive expansion of malignant B lymphocytes in peripheral blood. In spite of advances in sciences to recognize the number of effective agents for the treatment of chronic lymphocytic leuk...

journal_title：Journal of cancer research and therapeutics

authors： Abbaszadeh-Goudarzi K,Shokri F,Hosseini M,Jadidi-Niaragh F,Ghalamfarsa G,Saboor-Yaraghi AA

更新日期：2016-10-01 00:00:00

abstract：BACKGROUND:The effect of heparin in improving cancer survival has gained increasing attention over the past decades. Several clinical trials have evaluated the role of heparin on survival outcome and its safety profile in lung cancer patients. Thus, we performed a systematic review and meta-analysis from the results of...

journal_title：Journal of cancer research and therapeutics

authors： Yu Y,Lv Q,Zhang B,Lan F,Dai Y

更新日期：2016-10-01 00:00:00

abstract：OBJECTIVE:The objective of the study is to investigate whether hospital-based transitional care can reduce the postoperative complication in patients who received enterostomy or not by pooling the published prospective clinical studies. MATERIALS AND METHODS:Prospective clinical studies related to hospital-based trans...

journal_title：Journal of cancer research and therapeutics

authors： Chen Y,Jiang J,Wu Y,Yan J,Chen H,Zhu X

更新日期：2016-10-01 00:00:00

abstract：:The management of patients with the clinically negative neck (N0) in early oral cancers awaits a clear mandate despite growing evidence favoring elective neck dissection. Having a general policy of operating all N0 neck may indeed increase the number of unnecessary neck dissection in the true pathological N0 necks, a ...

journal_title：Journal of cancer research and therapeutics

authors： Rao VU,Patil PH,Rajaram BV

更新日期：2016-07-01 00:00:00

abstract：BACKGROUND:Wide variations are seen in clinical practice with respect to response to concurrent chemo radiation among cervical cancer patients. Fall in serum glutathione (GSH) level directly correlates with early response to treatment. Whether this early response translates to a better long term outcome is the subject ...

journal_title：Journal of cancer research and therapeutics

authors： Narasappa MG,Gururajachar JM,Chokkanna VK,Somashekar M

更新日期：2016-07-01 00:00:00

abstract：:[This corrects the article DOI: 10.4103/0973-1482.163868.]. ...

journal_title：Journal of cancer research and therapeutics

authors：

更新日期：2016-07-01 00:00:00

abstract：:Ovarian cancer has the most noteworthy lethal rate around gynecologic malignancies, and it is also considered as the fourth most frequent cancer in the woman in world. Two most critical barriers to treatment of ovarian malignancy are absence of early diagnostic markers and advancement of drug resistance after therapy,...

journal_title：Journal of cancer research and therapeutics

authors： Mirzaei H,Yazdi F,Salehi R,Mirzaei HR

更新日期：2016-04-01 00:00:00

abstract：AIM OF STUDY:The present work aimed to examine the efficacy of two ayurvedic formulations, Brahma Rasayana (BRM) and Chyavanaprash (CHM) to alleviate doxorubicin (DOX) induced acute cardiotoxicity. MATERIALS AND METHODS:Swiss albino mice were administered with DOX (25 mg/kg, i.p.) and two doses of BRM or CHM (1 and 2 ...

journal_title：Journal of cancer research and therapeutics

authors： AlSuhailbani E,Menon A,Nair CK

更新日期：2016-04-01 00:00:00

abstract：BACKGROUND:Somatic mutations of the epidermal growth factor receptor (EGFR) gene have been associated with tumor response to tyrosine kinase inhibitors (TKIs) and favorable outcome in patients with non-small-cell lung cancer (NSCLC). The activating mutations that confer sensitivity to EGFR TKIs are present in the TK do...

journal_title：Journal of cancer research and therapeutics

authors： Obeidat N,Awidi A,Ababneh N,Shomaf M,Al-Adaily T,Jaber M,Al-Khateeb M,Abbasi S

更新日期：2016-04-01 00:00:00

abstract：AIMS:Circulating extracellular micro ribonucleic acids (miRNAs) are considered as potential biomarkers for malignancy detection and diagnosis. The aim of this study was to determine whether circulating miRNA-148/152 family (miR-148a, miR-148b, and miR-152) expression in plasma could be used as potential biomarkers for ...

journal_title：Journal of cancer research and therapeutics

authors： Huang MX

更新日期：2016-04-01 00:00:00

abstract：AIMS:Several studies suggested that systemic lupus erythematosus (SLE) were associated with the risk of lung cancer. However, other studies did not confirm the result. Therefore, we conducted a meta-analysis to investigate this association. MATERIALS AND METHODS:A systematic literature search was conducted using the P...

journal_title：Journal of cancer research and therapeutics

authors： Wu Y,Hou Q

更新日期：2016-04-01 00:00:00

abstract：BACKGROUND:Ramucirumab, a fully human immunoglobulin G1 (IgG1) monoclonal antibody targeting vascular endothelial growth factor receptor-2 (VEGFR-2), has been approved for the treatment of advanced gastric cancer or gastroesophageal junction adenocarcinoma. Hypertension has been described as a common adverse event with...

journal_title：Journal of cancer research and therapeutics

authors： Qi WX,Fu S,Zhang Q,Guo XM

更新日期：2016-04-01 00:00:00

abstract：INTRODUCTION:Adenoid cystic carcinoma (ACC) is malignant neoplasm of the salivary glands. It accounts for most cases of minor salivary gland malignancies and a substantial proportion of parotid and submandibular gland malignancies. ACC is associated with a high mortality rate, and it often recurs after prolonged period...

journal_title：Journal of cancer research and therapeutics

authors： Jain A,Shetty DC,Rathore AS,Kumar K

更新日期：2016-04-01 00:00:00

abstract：BACKGROUND:Clinical significance of chloride intracellular channel 1 (CLIC1) in pancreatic ductal adenocarcinomas (PDAC) remains largely unknown. This study was performed to assess the expression of CLIC1 in benign and malignant pancreatic lesions, and to assess its clinicopathological significance. MATERIALS AND METH...

journal_title：Journal of cancer research and therapeutics

authors： Jia N,Dong S,Zhao G,Gao H,Li X,Zhang H

更新日期：2016-04-01 00:00:00

abstract：BACKGROUND:We seek to investigate whether carboplatin-based induction chemotherapy before modern day concurrent chemoradiotherapy (CCRT) improves survival in patients with bulky, locally advanced nonsmall cell lung cancer (NSCLC). MATERIALS AND METHODS:This analysis included 105 patients with Stage II and III NSCLC tr...

journal_title：Journal of cancer research and therapeutics

authors： Ahmed I,Ferro A,Baby R,Malhotra J,Cohler A,Langenfeld J,Aisner J,Zou W,Jabbour SK

更新日期：2016-04-01 00:00:00

abstract：PURPOSE:This retrospective study aims to assess the cut-off value of thyroglobulin (Tg) levels in nux or metastatic well-differentiated thyroid cancers (DTCs) with normal anti-Tg levels using with fluorodeoxyglucose/positron emission tomography/computed tomography (FDG PET/CT). MATERIALS AND METHODS:We reviewed FDG PE...

journal_title：Journal of cancer research and therapeutics

authors： Döner RK,Sager S,Görtan FA,Topuz ÖV,Akyel R,Vatankulu B,Baran A,Teksoz S,Sönmezoglu K

更新日期：2016-04-01 00:00:00

abstract：INTRODUCTION:The oncogenic form of anaplastic lymphoma kinase (ALK) gene is an attractive candidate marker for diagnostic and therapeutic purposes in several malignancies, including nonsmall cell lung cancer (NSCLC). This study aimed to examine the expression levels and clinical significance of ALK in a series of NSCLC...

journal_title：Journal of cancer research and therapeutics

authors： Roudi R,Haji G,Madjd Z,Shariftabrizi A,Mehrazma M

更新日期：2016-04-01 00:00:00

abstract：:[This corrects the article DOI: 10.4103/0973-1482.180080.]. ...

journal_title：Journal of cancer research and therapeutics

authors：

更新日期：2016-04-01 00:00:00

abstract：CONTEXT:The critical condition of the cancer patient and the stringent medical procedures do not often warrant the accessibility of the patient for psychological evaluation. Therefore, the study is conceptualized to assess the psychological problems of caregivers, which in turn have their impact upon cancer patients. ...

journal_title：Journal of cancer research and therapeutics

authors： Padmaja G,Vanlalhruaii C,Rana S,Nandinee D,Hariharan M

更新日期：2016-01-01 00:00:00

abstract：OBJECTIVE:Our experience with endoscopic surgery for vascular leiomyomas of the nasal septum was reviewed. PATIENTS AND METHODS:All patients with vascular leiomyomas of the nasal septum who were treated with endoscopic surgery from May 1995 to June 2007 were reviewed retrospectively. RESULTS:Twelve patients had vascu...

journal_title：Journal of cancer research and therapeutics

authors： Chen HH,Wang QY,Zhou SH

更新日期：2016-01-01 00:00:00

abstract：AIM OF STUDY:Embelin and celastrol, inhibitors of XIAP and NF-κB proteins respectively, have been derived from natural sources and shown anti-tumor activities against different cancer cell lines. Some interactions have recently been discovered between XIAP and NF-κB pathways, but the effects of these inhibitors in comb...

journal_title：Journal of cancer research and therapeutics

authors： Pazhang Y,Jaliani HZ,Imani M,Dariushnejad H

更新日期：2016-01-01 00:00:00

abstract：OBJECTIVE:To explore the outcome and prognostic factors of recursive partitioning analysis (RPA) Class III brain metastatic patients treated with stereotactic radiotherapy (SRT). MATERIALS AND METHODS:Fifty-six consecutive patients with metastatic brain tumors and Karnofsky performance scale (KPS) scores <70 treated w...

journal_title：Journal of cancer research and therapeutics

authors： Chen XJ,Xiao JP,Li XP,Jiang XS,Zhang Y

更新日期：2016-01-01 00:00:00

abstract：BACKGROUND:Gemcitabine is the first-line drug for nonsmall cell lung cancer, and 18F-fluorodeoxyglucose. (18F-FDG) and 18F-fluorothymidine. (18F-FLT) are positron emission tomography. (PET) imaging agents. The aim of this study was to explore the effect of gemcitabine on the uptake of 18F-FDG and 18F-FLT in A549 cells ...

journal_title：Journal of cancer research and therapeutics

authors： Zhang B,Deng SM,Guo LC,Dong JJ,Zhu YB,Gao Y,Wang ZX,Cho WC

更新日期：2016-01-01 00:00:00